Too many to list. A single best-of-all-time is simply not possible. The list would be endless. Just some off the top of my pointy head:
Walter White
Gaius Baltar/Cylon Model 6
Captain James T. Kirk/Commander Spock
Lt. Commander Data
Seven Of 69
Sam & Dean Winchester
Tony Soprano
George Costanza/Kosmo Kramer
Alex P. Keaton
Dan Fielding
Woody Boyd/Norm Peterson
Tyrion Lannister/Tywin Lannister/Jamie Lannister/Cersei Lannister
the Targaryen dragons
Darryl & Merle Dixon
Nucky Thompson/Richard Harrow/Gillian Darmody
Colonel/General Jack O'Neill
Sheldon Cooper
Uncle Phil/Cousin Carlton
Don Cherry
etc
etc
etc
It would be literally endless.